freephone 0800 862 0373
Sign in to view your quotes
Email address:
Password or PIN:

Forgotten your password? Reset it here.

New drug could cure rheumatoid arthritis by 'blindfolding' white blood cells

Published on 06/03/2012

Scientists have discovered a possible new method of treating rheumatoid arthritis, using a drug that ‘blindfolds’ white blood cells.

Rheumatoid arthritis is an autoimmune disease, meaning that your immune system attacks the cells that line your joints making them swollen, stiff and painful. Over time this can damage the joint, cartilage and nearby bone. White blood cells called T-cells are key players in this process.

The study, funded by the charity Arthritis Research UK, looked at the human-like immune system of a genetically engineered mouse with arthritis.

Researchers, writing in the journal Proceedings of the National Academy of Science, found that a compound called PS372424 blocked the ability of activated T-cells to invade joints. Only the specific T-cells implicated in rheumatoid arthritis are affected.

Study leader Dr Graeme O'Boyle, from the University of Newcastle, said; "Imagine that the damaged joint is covered in flags which are signalling to the white blood cells.

“Traditional treatments have involved pulling down the flags one by one but what we have done is use an agent which in effect 'blindfolds' the white blood cells."

"Therefore, they don't know which way to travel and so won't add to the damage."

Rheumatoid arthritis affects around 580,000 people in England and Wales. It is three times more common in women than in men. Whilst it is more common from the age of 40, it can affect people of any age, and gets worse with age.

The next stage for scientists is to improve the drug-like properties of PS372424 to prepare it for clinical trials. Further research could lead to an effective and inexpensive way of treating the condition.

Since arthritis is considered a chronic condition, it is unlikely that it will be covered by private medical insurance. However, if a cure is found for the condition it could be covered on your policy in the future, so compare health insurance online now.

Professor Alan Silman, medical director of Arthritis Research UK, said: “This research is very exciting, as although it is in its early stages, if it can be transferred to humans it could shut down the inflammation that causes rheumatoid arthritis.”

© ActiveQuote Ltd. 2012


Categories:  Medical
New drug could cure rheumatoid arthritis by 'blindfolding' white blood cellsScientists have discovered a possible new method of treating rheumatoid arthritis , using a drug that ‘blindfolds’ white blood cells. Rheu    tweet it on twittershare with your friends on Facebookshare with your friends on MySpaceBlog it on your LinkedIn profile
 

No.1 health insurance broker as rated by customers

I found the quality of service to be very helpful, and pretty much above my expectation. I'd recommend anyone to use ActiveQuote.

Review centre member

Very helpful and polite and always try their best to obtain the best quotes. Have been using them for the last 3 years and will continue to use them in the future.

Review centre member

A great service from the initial call, to finalising the agreement. I would highly recommend to my family and friends.

Review centre member

Proactive, efficient, and offered me insurance I need. I would say half price I would end up paying if I did it by myself. Many thanks.

Review centre member

Excellent service. Explained everything in detail and really helped to find the right insurance best suited to my needs - which wasn't necessarily the most expensive. 

Review centre member

Good value and the advisor was very helpful and recommended the best policy for my grandson. I would definitely use this service again and recommend to others.

Review centre member

We were contacted in good time to make a knowledgable choice. We were given plenty of options with lots of information to enable us to make the right choice.

Review centre member

The service I received was excellent, the staff member was very efficient and knowledgable. She went out of her way to get the best policy for me.

Review centre member

Great service. I really appreciated the help provided by Active Quote to arrange health insurance. The agent was very informative and proactive. Many thanks!

Review centre member

I received excellent care and attention from the first phone call till the last. Friendly, efficient and patient.

Review centre member
 
This site is operated by Insurance Broker ActiveQuote Ltd registered in England & Wales company number 6765845.
Authorised and Regulated by the Financial Conduct Authority (FCA). Firm reference number 501109 as detailed on the Financial Services Register. Please read our Key Facts document.
For information about your rights as a consumer visit Citizens Advice.

Our insurance comparison service is free and easy for you to use, but you are responsible for making sure all your information is entered correctly, and for choosing your insurer.

This site uses cookies in order to work correctly - these are not harmful and do not contain personal information. By using this site you consent to this. I understand  Tell me more

please wait ...